i live in oakland, but i lived in sf for 7 years, and i still work there too. there's definitely a lot of great things to check out. anything in particular that you are into and would want to see?
a list of my favorite things would be:
-the academy of science in golden gate park.
-conservatory of flowers in golden gate park.
-walking across golden gate bridge.
-walkin' and shoppin' in china town.
-baker beach. beautiful view of golden gate bridge.
-dolores park in the mission. this is where all the sf locals and hipsters hang out on most days, especially nice ones. great spot for people watching and a general idea of sf culture, i guess...
music venues to check out:
-the great american music hall
-slim's
-the hemlock
-bottom of the hill
-the eagle tavern
-submission art gallery
-the knockout
-the regency ballroom
good bars:
-zeitgeist... directly next door to blackheart tattoo.
-the buckshot... great collection of original hand painted flash from current and past tattooers including sailor jerry, heath preheim and more.
-molotov's... good local bar across the street from idle hand tattoo.
-the kilowatt. locals bar.
hell, i could go on and on....