Being stimulants that impact the central nervous system, it is typically not advised to use Modalert 200mg (modafinil) and caffeine together without a doctor's supervision. While coffee inhibits adenosine receptors to lessen tiredness, Modalert increases alertness by raising dopamine and norepinephrine. When used combined, they may cause overstimulation, which may cause jitters, anxiety, restlessness, and elevated heart rate. Increased blood pressure, sleeplessness, and dehydration might all be made more likely by the combined effects. If Modalert 200 doesn't work for you, it's better to talk to your doctor about other options rather than depending on caffeine.
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